When President Biden said in a national address earlier this month that barbecues and in-person get-togethers might be possible for the July 4 holiday, many Americans became hopeful that they might reclaim another summer tradition: the vacation.

Even before the president’s cautiously optimistic speech, online search and booking activity for summer travel was breaking records. On Hopper, a travel booking app, there’s been a nearly 75 percent increase in searches for late-summer flights since late February, when the third vaccine was approved for the United States. The travel search site KAYAK is also seeing interest for summer travel steadily increase, with search traffic on its site growing as much as 27 percent each week.

As for bookings, Hopper reports that domestic bookings are up 58 percent so far this month compared to all of March 2019. More Americans, it seems, are planning sunshine breaks, reunions with grandchildren or just getting away.

“We will literally go anywhere, we’re so desperate to travel,” said Minda Alena, a New Jersey-based interior designer and creative director who is in the process of planning four trips this summer and fall. “We just want to get on a plane and feel like we’ve stepped away from our lives for a week.”

Her vacations will begin with an August trip to Turks & Caicos, a destination that has been on Ms. Alena’s bucket list for years. A visit to Jamaica with her husband will come next, followed by a girls’ getaway to Palm Beach, Fla., for her 50th birthday, and a family trip with her three children to Greece before the end of the year.

Ms. Alena, 49, and her husband are both newly vaccinated. They have lost friends in the pandemic, but she said she feels lucky that no one in her family has gotten sick. The last year, however, has changed how her family views their finances: They are more inclined, she said, to take some of the money they have spent years saving and invest it in experiences.

“My husband and I are both like, ‘What are we waiting for?’ Life is too short,” she said.

The pandemic decimated the travel industry last year: The Organization for Economic Co-operation and Development predicted a decrease in the global tourism economy of up to 80 percent after accounting for all of 2020’s data. But with the pace of vaccinations accelerating and travel numbers ticking up, a rebound — at least in domestic travel — feels imminent.

A poll conducted by Amazing America, a website dedicated to the American road trip, found that more than 75 percent of respondents believe it will be safe to travel this summer. (More than 68 percent said the pandemic has pushed them to choose domestic travel over international.)

Pre-pandemic, the average booking window for domestic travel in the United States was between 45 and 60 days before departure. In 2020, however, that window shrunk down to just six or seven days, according to data from Priceline. Hesitancy over quarantine rules, concerns about sickness and economic uncertainty were all factors for those few who were vacationing.

Halee Whiting, the owner of the hotel sales consultancy Hospitality With a Flair, creates pricing strategies and tailored packages for hotel brands. Nearly 70 percent of the web traffic for her clients, she said, is now for travel between July and mid-September.

“People are itching to get out, but they’re still hesitant,” she said. “With the vaccine being more prevalent and states starting to loosen their guidelines, this summer will be when they are ready to tiptoe out of their bubble.”

Indeed, many travel agencies and lodging operators are already seeing numbers that outpace 2019, which was a banner year for the travel industry.

Vacasa, the rental home-management site, reports its reservations are up more than 300 percent over last year. Stand-alone rental cottages were a big draw for vacationers in 2020 — thanks to their promise of privacy — and this summer travelers are again snapping them up.

Take a look at just one of Vacasa’s properties, the Whispering Pines Lodge in Eagle River, Pa. Bookings at the 11-bedroom lodge are 97.5 percent higher than they were at this point two years ago, with occupancy for the summer already at nearly 100 percent.

Hotels, which are still experiencing a year-over-year decrease in occupancy of more than 20 percent, are also welcoming this summer rush.

“August usually fills up late, but we’re already at almost 50 percent occupancy for August,” said Phil Baxter, the owner of Sesuit Harbor House, a 21-room inn in East Dennis on Cape Cod. “There’s a human need to gather, and sharing joy and sorrow is something you do with people, not by yourself.”

Hotels that opened in the midst of the pandemic are seeing a much-needed boost, as well. The Inn at the Mission San Juan Capistrano, which opened Sept. 1 next to the ruins of the historic Mission San Juan Capistrano in Southern California, has seen new weekly bookings double compared to the last four months.

The Roxbury at Stratton Falls, a whimsical resort in the Catskills with intricate themed cottages, came very close to shutting down for good after its summer 2020 opening was met with a flurry of cancellations.

“This year we’re facing the opposite problem,” said Greg Henderson, a co-owner. “Demand is so high that by mid-April there will be no weekend availability all the way through October.”

“Demand is real,” said Betsy O’Rourke, the chief marketing officer for Xanterra Travel Collection, which manages lodges and restaurants at national parks, including the Grand Canyon National Park and Mount Rushmore National Memorial. “We are sold out for most dates throughout the summer and fall.”

Many travelers are booking trips in a bid to finally have the celebrations that were dampened or outright canceled in 2020, and hotels and tour operators are gladly leaning into the trend. The Langham New York will fill a hotel room with balloons and champagne for travelers who want to celebrate — or do over — a birthday or anniversary; another nearby hotel, the Baccarat New York, offers a similar package that includes a personalized gift to commemorate a guest’s 2020 missed milestone.

No travel sector has been harder hit by the pandemic than cruises, and most major cruise lines aren’t even considering restarting U.S. sailings until the fall.

But customers are nevertheless booking for later in the year, especially on smaller ships. Uniworld, a boutique river cruise operator, runs a Christmas-themed European cruise down the Danube every winter; this year they are also launching two special Christmas in July cruises for travelers who felt that their 2020 Christmas was a wash.

John Capps, 65, a clinical psychologist who lives in Northern Virginia, eagerly booked the July cruise with his wife and another couple. Mr. Capps and his wife are both Covid-19 long-haulers who were still battling residual symptoms in December; their Christmas was somber and muted.

“There was no party, no gatherings,” he said. “We’re damn lucky — we’re not back to 100 percent but we’re fully functional, and we didn’t lose an income stream in the pandemic. But we’re very excited to have this summer trip that will also give us Christmas.”

For those looking to travel this summer but not sure when they should pull the purchase trigger, travel advisers say that the longer you wait, they more you’ll spend.

“Prices are starting to move up, but there are still a lot of deals to be found,” said Brett Keller, Priceline’s chief executive. “Hotel prices, for example, continue to be discounted almost 20 percent versus the past several years, with the greatest discounts still available at higher quality 3- and 4-star hotels.”

And Adit Damodaran, the economist at Hopper, predicts that airfare prices will begin to climb in April before topping out in early summer. “Typically we see a gradual rise from mid-April to July, where flights are steadily more expensive the closer they are to summer. This year it looks like a wave rolling in,” he said.

Another reason to book now? Most of the flexible booking policies introduced at the beginning of the pandemic remain in place, allowing travelers to change or cancel hotel and airfare reservations without incurring huge fees.

“As long as our customers have the ability to cancel and only pay a small penalty, they’re booking,” said Sudeep Shah, chief executive of Travel King International, a travel agency in Dallas. “There’s a lot of people who are making up for what they lost.”

Mr. Henderson, of The Roxbury at Stratton Falls, admits it’s hard to trust the optimistic signs for his business after such a difficult year. While he was fighting for his business in New York, his brother in Oklahoma nearly died of Covid.

“We all have a form of PTSD,” he said.

But both he and his husband were able to receive their first shot of the Covid-19 vaccine this month after eligibility in New York was expanded to hotel workers. Two weeks after he receives his second shot, he said, he is going to plan a trip to Oklahoma to see his brother.

“I’m not saying I’m buying it yet, but I am looking,” he said. “There’s a kind of euphoria. And if I’m feeling that way, I know plenty of other people must be feeling the same way too.”

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